• Research Interest
• Clinical Specialties
• Recent Publications
• Honors & Awards
• Training and Certifications
• Contact Information

Research Interest

• Genetic basis of inherited leukemia
• Hematopoietic malignancies

Clinical Specialties

• Leukemia

Recent Publications (selected)

• Aiyagari A, Taylor B, Aurora V, Young SG, Shannnon KM. Hematologic effects of inactivating the Ras processing enzyme Rce1. Blood 2003; 101: 2250-2252.
• Wong S, McLaughlin J, Cheng D, Shannon K, Robb L, Witte ON. IL-3 receptor signaling is dispensable for BCR-ABL-induced myeloproliferative disease. Proc Natl Acad Sci USA 2003; 100: 11630-11635.
• Loh ML, Vattikuti S, Reynolds MG, Carlson EJ, Schubbert S, Lieuw KH, Cheng JW, Stokoe D, Bonifas JM, Curtiss NP, Gotlib J, Meshinchi S, Le Beau MM, Emanuel PD, Shannon KM. Somatic mutations in PTPN11 implicate the protein tyrosine phosphatase SHP-2 in leukemogenesis. Blood 2004; 103: 2325-2331.
• Braun BS, Tuveson DA, Kong N, Le DT, Kogan SC, Rozmus J, Le Beau MM, Jacks TE, Shannon KM. Somatic activation of oncogenic Kras in hematopoietic cells induces a fatal myeloproliferative disorder. Proc Natl Acad Sci USA 2004; 101: 597-602.
• Side LE, Curtiss NP, Teel K, Kratz C, Wang PW, Larson RW, Le Beau MM, Shannon KM. RAS, FLT3, and TP53 Mutations in therapy-related myeloid malignancies with abnormalities of chromosomes 5 and 7. Genes Chromosomes Cancer 2004; 39: 217-223.
  

Honors & Awards (selected)

• Ross Outstanding Young Investigator Award, Western Society for Pediatric Research, 1994
• Nycomed Research Award of the International Society for Pediatric Oncology (SIOP), 1993
• American Academy of Pediatrics Award for Excellence in Pediatric Research, 1998
• Roma and Marvin Auerback Distinguished Professor of Molecular Oncology, 2000

Training & Certificates

• Cornell University Medical Degree
• University of Texas, Southwestern Residency
• UCSF Pediatric Hematology/Oncology Fellowship