• Research Interest
• Clinical Specialties
• Recent Publications
• Honors & Awards
• Training and Certifications
• Contact Information

Research Interest

• Defining the underlying mechanisms in the development of lymphoid malignancies, including leukemia and lymphoma.
  
• Immune-mediated cytopenias, hemophagocytoic lymphohistocytosis (HLH), post-transplant lymphoproliferative disorders (PTLD)

Clinical Specialties

• Leukemia
• Lymphoma
• Immune-mediated cytopenias

Recent Publications (selected)

• Hermiston, M.L., and Gordon, J.I. Functional organization of the crypt-villus axis and evolution of its stem cell hierarchy during intestinal development. Amer. J. Physiol., 268 (Gastrointest. Liver Physiol. 31):G813-G822 (1995)
  
• Hermiston, M.L., and Gordon, J.I. Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin. Science, 270:1203-1207 (1995)
  
• Hermiston, M.L., Wong, M.H., and Gordon, J.I. Forced expression of E-cadherin in the mouse intestinal epithelium slows cell migration and provides evidence for non-autonomous regulation of cell fate in a self-renewing system. Genes and Development, 10:985-996 (1996) (Selected for cover)
• Wong, M.H., Hermiston, M.L., Snider, D., and Gordon, J.I. Forced expression of the tumor suppresser adeneomatosis polyposis coli protein induces disordered cell migration in the intestinal epithelium. Proc. Natl. Acad. Sci. USA, 93:9588-9593
  (1996)
  
• Fazeli, A., Dickinson, S.L., Hermiston, M.L., Tighe, R., Steen, R.G., Small, C.G., Stoeckli, E.T., Keino-Masu, K., Masu, M., Rayburn, H., Simons, J., Bronson, R.T., Gordon, J.I., Tessier-Lavigne, M., and Weinberg, R.A. Phenotype of mice lacking Deleted in colorectal cancer (DCC) gene. Nature, 386:796-804 (1997)
• Hermiston, M.L., Xu, Z, Majeti, R, and Weiss, A. Reciprocal regulation of tyrosine phosphorylation by protein tyrosine kinases ad protein tyrosine phosphatases. J. Clin. Invest., 109:9-14 (2002)
• Hermiston, M.L. and Mentzer, W.C. Approach to the Anemic Child. Pediatr. Clin. North Amer., 49:877-91 (2002)
• Hermiston, M.L., Xu, Z., and Weiss, A. CD45: A critical regulator of signal transduction thresholds in immune cells. Annual Review in Immunology, 21:107-137 (2003)
• Hermiston, M.L., Tan, A., Gupta, V, Majeti, R., and Weiss, A. The juxtamembrane wedge negatively regulates CD45 function in B cells. Immunity, in press, (2005)
  

Honors & Awards (selected)

• 2003 NIH Clinical Investigator Award (K08)
• 2001 Molecular Oncology Investigator, University of California San Francisco Cancer Center
• 2000 Housestaff Teaching Award, selected by University of California San Francisco Class of 2000 Medical School Class for teaching excellence
• 1997 UCSF Molecular Medicine Research Fellowship Program
• 1997 Alpha Omega Alpha, Washington University School of Medicine
• 1997 Missouri State Medical Association Award, awarded to an Honors Graduate for outstanding achievement in the study of medicine

Training & Certificates

• Washington University School of Medicine, Medical Degree, Ph.D.
• UCSF Medical Center, Pediatric Residency
• UCSF Medical Center, Pediatric Hematology/Oncology Fellowship