Bittoo Kanwar, M.D.

• Research Interest
• Clinical Specialties
• Recent Publications
• Honors & Awards
• Training and Certifications
• Contact Information

Research Interests

• Inflammatory Bowel Disease (IBD):
• The role of adaptive immunity on disease progression
• Investigating novel therapeutic targets in small animal models of disease
• HIV Disease:
• Research involves studying the role of mucosal immune cells as a determinant of disease progression. Working in the laboratory of Professor Joseph “Mike” McCune, M.D., Ph.D., in the UCSF Division of Experimental Medicine
• Collaborating on non-human primate studies of simian immunodeficiency virus (SIV) disease and the mucosal response in acute infection
• Immune Imaging:
• Current studies investigate the utility of positron emission tomography (PET) combined with radiolabeled whole antibodies or protein fragments in small animal models of IBD
• Active collaboration with Genentech, Inc

Clinical Specialties

• Inflammatory bowel disease
• Immunodeficiency associated intestinal disease
• General pediatric gastroenterology and nutrition

Recent Publications (selected)

• Kanwar B, Gao DW, Hwang AB, Grenert JP, Williams SP, Franc B, McCune JM.  In vivo imaging of mucosal CD4+ T cells using single photon emission computed tomography in a murine model of colitis. J Immunol Methods. 2008; 329(1-2):21-30.
  
  
• Favre D, Lederer S,* Kanwar B,* Min Ma Z,* Proll S, Kasakow Z, Mold J, Swainson L, Barbour JD, Baskin CR, Palermo R, Pandrea I, Miller C, Katze M, McCune JM. Critical loss of the balance between TH17 and T regulatory cell populations in pathogenic SIV infection (*co-equal authors). PLoS Pathogens. 2009 Feb;5(2):e1000295. Epub 2009 Feb 13
  
  
• Lederer S,* Favre D,* Walters K-A, Proll S, Kanwar B, Kasakow Z, Baskin CR, Palermo R, McCune JM, Katze MG. Transcriptional profiling reveals significant distinctions in kinetics and tissue compartmentalization between pathogenic and non-pathogenic SIV infection. PLoS Pathogens. 2009 Feb;5(2):e1000296. Epub 2009 Feb 13
  
  
• Cheng L, Kanwar B, Tcheurekdjian H, Grenert JP, Muskat M, Heyman MB, McCune JM, Wara DW. Persistent systemic inflammation and atypical enterocolitis in patients with NEMO syndrome. Clinical Immunology. 2009. Jul;132(1):124-31

Honors & Awards (selected)

• 2005: Rush University Teaching Resident of the Year
• 2006: NIH Pediatric Research LRP Award
• 2009: NIH Clinical Scientist Development Award (K08)

Training & Certificates

• University of Minnesota, B.S. (1998)
• University of Iowa, M.D. (2002)
• Rush University, Pediatric Residency (2002-2005)
• University of California, San Francisco, Pediatric GI, Hepatology, and Nutrition Fellowship (2005-2009)
• Visiting Scientist, Genentech, Inc. (2006-present)
• Board Certified in Pediatrics (2006)