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G - R A F S
(Growth – Rates And Feeding with Synbiotics) seeks to assess the growth of infants fed a formula with a level of protein closer to breast milk
 
G-RAFS growth – rates and feeding with synbiotics study currently recruiting participants!
 
Call Toll-Freeor E-mail
866-913-8477 GRAFS@ucsf.edu
 

G-RAFS is seeking parents of infants to participate in a study to assess the growth of infants who are fed a formula with a level of protein closer to breast milk, as compared to the growth of infants fed formula with a standard level of protein.

Background

G-RAFS is a national multi-site, double-blind, randomized control study. The goal of this study to assess the growth of infants who are fed a formula with a level of protein closer to breast milk (with and without synbiotics), as compared to the growth of infants fed formula with a standard level of protein. Breastfeeding represents the “gold standard” for infant health, and efforts are being made to support breast feeding at both the international and local levels. After breast milk, infant formulas are the next best source of nutrition for newborn and growing infants, and attempts are being made to match the health advantages of breast feeding for infants who are fed formula.



What are synbiotics?

Synbiotics are being added to formula in an effort to positively influence the type of intestinal flora or “bacteria in the gut”. We hypothesize that this type of formula will make the intestinal flora similar to the intestinal flora of breastfed infants. Synbiotics are a dietary supplement that contains a mixture of beneficial bacteria called probiotics and fiber that does not dissolve called prebiotics. Probiotics are live bacteria found in many foods especially in cultured foods like yogurt. Probiotics live in the gut naturally and prebiotic-like substances are found in large quantities in breast milk.



What synbiotic is being used in this study?

The synbiotic used in this study is Bifidobacterium lactis combined with galacto-oligosaccharride. In full-term infants, breastfeeding induces the development of Bifidobacterium in the gut and remains the dominant organism in the gastrointestinal tract of the infant until weaning. When added to infant formula, synbiotics may provide some of the same health benefits that are provided by the consumption of human milk.



Am I eligible to participate in the G-RAFS study?

You may be eligible if you are expecting a baby and you have elected to use formula to feed your baby.
 
Call Toll-Freeor E-mail
866-913-8477 GRAFS@ucsf.edu
 
 

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Updated: August 18, 2010
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